The system described in the 2026 publications (often referred to as the ULTRA system) provides an unprecedented combination of field-of-view (FOV) and depth. Multi-scale in vivo neuronal imaging.

The ULTRA system is specifically designed for complex, multi-regional brain studies.

Employs advanced scanning techniques to achieve a total imaged volume of over 45 mm³. 3. Key Applications in Neuroscience

The system sequences through Zernike modes to compensate for aberrations, with optimization processes sometimes completing in minutes, tailored for high-speed scanning (e.g., 133 Hz for ROI).