Tg2 | Direct

🔬 TG2: The Molecular "Swiss Army Knife" Shaping Cellular Fate

TG2 acts as a "molecular glue," crosslinking extracellular collagen and fibronectin to help stabilize tissue structure, making it vital for wound healing. 🔬 TG2: The Molecular "Swiss Army Knife" Shaping

Because TG2 is implicated in chronic conditions like cancer and neurodegeneration (such as Huntington's and Alzheimer's), it is now a hot target for new therapeutic drugs designed to selectively inhibit its activity without harming healthy cells. TG2 is a multifunctional

Often referred to as tissue transglutaminase, TG2 is a multifunctional, Ca²⁺-dependent protein that acts far beyond a simple crosslinker. It’s an enzyme that wears many hats: 🔬 TG2: The Molecular "Swiss Army Knife" Shaping