[s2e2] Enough Is Enough (no More Tears) May 2026

: Devastated by the revelation, she begins to distance herself from Derek, famously telling him to "take care of her" (referring to Addison).

: Her presence creates immediate tension as she begins to establish herself at the hospital, prompting Derek to involve Richard’s wife, Adele Webber , in the situation. Episode Details Air Date : October 2, 2005 Director : Peter Horton

: Ellen Pompeo (Meredith), Patrick Dempsey (Derek), Sandra Oh (Cristina), T.R. Knight (George), and Katherine Heigl (Izzie).

: Grapples with her relationship with Burke, particularly after discovering she is pregnant, which she attributes to her newfound emotional vulnerability.