Quinones — Reactions Of Substituted

Substituted quinones are some of the most versatile electrophiles in organic chemistry. Because the quinone core is electron-deficient, their reactivity is largely governed by the nature and position of the substituents ( -groups) attached to the ring. 1. Nucleophilic Conjugate Addition (Michael Addition)

Large groups can hinder the approach of the diene, often dictating which face of the quinone is attacked. reactions of substituted quinones

If the quinone has a good leaving group (like a halogen in p-chloranil ), a nucleophile can displace it directly. This is a common route for synthesizing complex dyes and bioactive molecules. 5. Photochemical Reactions Substituted quinones are some of the most versatile

This is the most common reaction for substituted quinones. A nucleophile (like an amine, thiol, or alcohol) attacks the double bond. or alcohol) attacks the double bond.