: Despite the aggressive reduction, the process is bit-for-bit lossless. Using the Genozip platform , users can reconstruct the original FASTQ and BAM files exactly as they were. Performance and Impact
: Containing those same reads mapped to a reference genome. 15p.zip
While a standard .zip file uses the (a combination of LZ77 and Huffman coding) to find repeated patterns within a single stream of data, Genozip’s Deep method is domain-specific. It understands the structure of genomic data, allowing it to achieve compression ratios that general-purpose tools cannot match. : Despite the aggressive reduction, the process is
: Instead of compressing FASTQ and BAM files as independent silos, Deep exploits the fact that the BAM file is essentially a reorganized version of the FASTQ data. While a standard
Because BAM files originate from FASTQ files, they contain nearly identical sequence information, creating a massive that traditional compression (like GZIP or BGZF) treats as separate, redundant data. The "Deep" Compression Method
: Decompression is handled automatically by standard Genozip commands like genounzip (to restore the full set) or genocat (to extract a specific file). Comparison: Deep vs. Standard ZIP